This is the first in a series of regular updates on the Ebola Response Roadmap. The update contains a review of the epidemiological situation and response monitoring. This first update provides a baseline against which progress on the full implementation of the roadmap can be measured against core Roadmap indicators over time. Additional indicators will be reported as data are consolidated.

The data contained in this report are based on the best information currently available. Substantial efforts are being made to improve the availability and accuracy of information about both the epidemiological situation and the response implementation.

Following the roadmap structure, country reports fall into three categories: those with widespread and intense transmission (Guinea, Liberia, and Sierra Leone); those with an initial case or cases, or with localized transmission (Nigeria); and those sharing land borders with areas of active transmission (Benin, Burkina Faso, Côte d’Ivoire, Guinea-Bissau, Mali, Senegal) and those with international transportation hubs.

The total number of probable, confirmed and suspect cases in the current outbreak of Ebola virus disease (EVD) in West Africa is 3052, with 1546 deaths. Countries affected are Guinea, Liberia, Nigeria, and Sierra Leone.1 The figure below shows the number of cases by country that have been reported between the beginning of January 2014 (epidemiological week 1) and 25 August 2014 (epidemiological week 34).

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